Purple Yam Extract (Dioscorea Alata L.) As Adjuvant Antihipertension Medicine for Postpartum Hipertension
DOI:
https://doi.org/10.30994/sjik.v9i2.363Keywords:
Purple Yam Extract, Blood Pressure, Hypertension, PostpartumAbstract
One third of women who have hypertension in pregnancy will continue to have high blood pressure during the postpartum period. Potential adjuvant pharmacological therapy is needed, one of them is purple yam extract which contains flavonoids and dioscorin. This type of research is a quasi experiment. The research respondents consisted of 16 people treated with purple yam extract 320 mg/day and nifedipine 10 mg/day and 16 people were given nifedipin 10 mg/day for 14 days. The results of the study were the systolic of the intervention group decreased by 28.12 mmHg and the control group decreased by 8.94 mmHg with a p-value of 0,000. The diastolic of the intervention group decreased by 18.43 mmHg and the control group decreased by 3.75 mmHg with a p-value of 0,000. The conclusion of this study is purple yam extract has the potential as an alternative therapy to reduce blood pressure in postpartum hypertension.
References
Ghuman, N., Rheiner, J., Tendler, B. E., & White, W. B. (2009). Hypertension in the Postpartum Woman: Clinical Update for the Hypertension Specialist. The Journal of Clinical Hypertension, 11(12), 726–733.
Hsu, F. H., Y. H. Lin, M. H. Lee, C. L. Lin, and W. C. Hou. (2002). Both Dioscorin, The Tuber Storage Protein of Yam (Dioscorea alata CV Tainong No. 1), and its Peptic Hydrolysates Exhibited Angiostensin Converting Enzyme Inhibitory Activities. J. Agric.Food Chem, 50, 6109-6113.
Ismalia N, Zuraida R. (2016). Effect Tomato (Lycopersion esculentum Mill) for Decreasing High Blood Pressure. MAJORITY, 5(4), 107-111.
Kementrian Kesehatan Republik Indonesia. Profil Kesehatan Indonesia 2017. (2018). Jakarta: Kementerian Kesehatan Republik Indonesia.
Liu, Y.H., Lin, Y.-S., Liu, D.-Z., Han, C.-H., Chen, C.-T., Fan, M., & Hou, W.-C. (2009a). Effects of Different Types of Yam (Dioscorea alata) Products on the Blood Pressure of Spontaneously Hypertensive Rats. Bioscience, Biotechnology, and Biochemistry, 73(6), 1371–1376.
Liu, Y. M. and K. W. Lin. (2009b). Antioxidative ability, dioscorin stability, and the quality of yam chips from various yam species as affected by processing method. Journal of Food Science, 74(2), C118-C125.
Nadila F. (2014). Antihypertensive Potential of Chayote Fruit Extract for Hypertension Treatment. J Majority, 3(7), 34-38.
Nzelu, D. (2018). Dumitrascu-Biris, D., Hunt, K. F., Cordina, M., & Kametas, N. A. Pregnancy outcomes in women with previous gestational hypertension: A cohort study to guide counselling and management. Pregnancy Hypertension, 12, 194–200.
Prasetya, Estiasih Teti, Nugrahini Nur Ida Panca. (2016). Potensi Tepung Ubi Kelapa Ungu dan Kuning. Jurnal Pangan dan Agroindustri, 4(2), 468-473.
Say L, Chou D, Gemmill A, Tunçalp Ö, Moller AB, Daniels JD, et al. (2014). Global Causes of Maternal Death: A WHO Systematic Analysis. Lancet Global Health, 2(6), e323-e333.
Sharma KJ GN. (2017). Oral Labetalol Compared to Oral Nifedipin for Postpartum Hypertension: A randomized controlled trial. Hypertension in Pragnancy, 36(1), 44-47.
Smith, M., Waugh, J., & Nelson-Piercy, C. (2013). Management of postpartum hypertension. The Obstetrician & Gynaecologist. 15(1), 45–50.
